查看“︁羟甲基”︁的源代码

{{Chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 386006473
| IUPACName = Hydroxymethyl
| ImageFile = Hydroxymethyl group skeletal.svg
| ImageSize = 200px
|Section1={{Chembox Identifiers
| CASNo_Ref = {{cascite|correct|??}}
| CASNo = 2597-43-5
| PubChem = 137654
| ChemSpiderID = 121313
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| SMILES = [CH2]O
| StdInChI = 1S/CH3O/c1-2/h2H,1H2
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = CBOIHMRHGLHBPB-UHFFFAOYSA-N
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
}}
|Section2={{Chembox Properties
| Formula = -{{chem|CH|2|OH}}
| MolarMass = 31.03
}}
|Section3={{Chembox Thermochemistry
| DeltaHf = -9 kJ mol<sup>−1</sup>
}}
}}

在[[有机化学]]中，'''羟甲基'''是一种结构式为<chem>-CH_2-OH</chem>的取代基，它由[[亚甲基]]（<chem>-CH_2</chem>）和[[羟基]]（<chem>-OH</chem>）组成。羟甲基与甲氧基（<chem>-O-CH_3</chem>）有相同分子式，但化学性质不同。<ref>{{Cite journal |title=NAMING ORGANIC COMPOUNDS |url=https://www.kpu.ca/sites/default/files/downloads/sup08.pdf |url-status=live |journal= |volume=37 |issue=1 |pages=10 |archive-url=https://web.archive.org/web/20220721055000/https://www.kpu.ca/sites/default/files/downloads/sup08.pdf |archive-date=2022-07-21 |access-date=2022-08-08}}</ref><ref>{{Cite journal |last1=Dong |first1=Hao |last2=Zheng |first2=Erjin |last3=Niu |first3=Zhiyin |last4=Zhang |first4=Xiaoyu |last5=Lin |first5=Yi-Yu |last6=Jain |first6=Priyesh |last7=Yu |first7=Qiuming |date=2020-04-15 |title=Hydroxymethyl-Functionalized PEDOT-MeOH:PSS for Perovskite Solar Cells |url=https://pubmed.ncbi.nlm.nih.gov/32204591/ |url-status=live |journal=ACS Applied Materials & Interfaces |volume=12 |issue=15 |pages=17571–17582 |doi=10.1021/acsami.0c01756 |issn=1944-8252 |pmid=32204591 |s2cid=214630308 |archive-url=https://web.archive.org/web/20220808221741/https://pubmed.ncbi.nlm.nih.gov/32204591/ |archive-date=2022-08-08 |access-date=2022-08-08}}</ref>

羟甲基是[[丝氨酸]]（一种编码氨基酸）的[[侧链]]。<ref>{{Cite journal |last1=Perczel |first1=András |last2=Farkas |first2=Ödön |last3=Csizmadia |first3=Imre G. |date=1996-01-01 |title=Peptide Models. 18. Hydroxymethyl Side-Chain Induced Backbone Conformational Shifts of l -Serine Amide. All ab Initio Conformers of For- l -Ser-NH 2 |url=https://pubs.acs.org/doi/10.1021/ja960464q |url-status=live |journal=Journal of the American Chemical Society |language=en |volume=118 |issue=33 |pages=7809–7817 |doi=10.1021/ja960464q |issn=0002-7863 |archive-url=https://web.archive.org/web/20220808210908/https://pubs.acs.org/doi/10.1021/ja960464q |archive-date=2022-08-08 |access-date=2022-08-08}}</ref>

== 参见 ==
* [[官能团]]
* [[羟基]]
* [[甲氧基]]

==参考资料==
{{reflist}}
{{官能团}}
[[Category:取代基]]
[[Category:羟甲基化合物|*]]

{{Organic-compound-stub}}