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烯醇化酶
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{{enzyme | Name = phosphopyruvate hydratase | EC_number = 4.2.1.11 | CAS_number = 9014-08-8 | IUBMB_EC_number = 4/2/1/11 | GO_code = 0004634 | image = Enolase 2ONE wpmp.png | width = | caption = Yeast enolase dimer.<ref name="pmid9376357">{{PDB|2ONE}}; {{cite journal | vauthors = Zhang E, Brewer JM, Minor W, Carreira LA, Lebioda L | title = Mechanism of enolase: the crystal structure of asymmetric dimer enolase-2-phospho-D-glycerate/enolase-phosphoenolpyruvate at 2.0 A resolution | journal = Biochemistry | volume = 36 | issue = 41 | pages = 12526–34 | date = October 1997 | pmid = 9376357 | doi = 10.1021/bi9712450 }}</ref> }} {{Infobox protein family | Symbol = Enolase_N | Name = Enolase, N-terminal domain | image = PDB 1pdz EBI.jpg | width = | caption = x-ray structure and catalytic mechanism of lobster enolase | Pfam = PF03952 | Pfam_clan = CL0227 | InterPro = IPR020811 | SMART = | PROSITE = PDOC00148 | MEROPS = | SCOP = 1els | TCDB = | OPM family = | OPM protein = | CAZy = | CDD = }} {{Pfam box | Symbol = Enolase | Name = Enolase | Pfam = PF00113 | InterPro = IPR000941 | PROSITE = PDOC00148 | PDB = {{PDB|1e9i}} {{PDB|1ebg}} {{PDB|1ebh}} {{PDB|1els}} {{PDB|1iyx}} {{PDB|1l8p}} {{PDB|1nel}} {{PDB|1oep}} {{PDB|1one}} {{PDB|1p43}} | image = 2XSX.pdb.png | width = | caption = Crystal structure of dimeric beta human enolase [[ENO3]].<ref name="Vollmar_2010">{{PDB|2XSX}}; {{cite journal |vauthors=Vollmar M, Krysztofinska E, Chaikuad A, Krojer T, Cocking R, Vondelft F, Bountra C, Arrowsmith CH, Weigelt J, Edwards A, Yue WW, Oppermann U |title = Crystal structure of human beta enolase ENOB | journal = To be published | year = 2010}}</ref> }} '''烯醇化酶'''({{lang-en|Enolase}},又被称为'''磷酸烯醇式丙酮酸水合酶''',{{lang|en|phosphopyruvate hydratase}})是负责催化[[糖酵解]]的第九步反应,[[2-磷酸甘油酸]](2-PG)转化为[[磷酸烯醇式丙酮酸]](PEP)的[[金属蛋白|金属酶]]。其催化的化学反应式为: :2-磷酸-D-甘油酸 <math>\rightleftharpoons</math> 磷酸烯醇式丙酮酸 + H<sub>2</sub>O 烯醇化酶[[裂合酶]]家族中的水裂解酶类,用于裂解碳氧键。 == 参考文献 == {{Reflist|33em}} == 外部链接 == * {{MeshName|Enolase}} {{糖酵解}} {{碳-氧裂合酶}} {{糖酵解酶类}} [[Category:兼职蛋白质]]
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