查看“︁L-木酮糖还原酶”︁的源代码

{{DISPLAYTITLE:<small>L</small>-木酮糖还原酶}}
{{enzyme
| Name = <small>L</small>-木酮糖还原酶
| Systematic_name = xylitol:NADP<sup>+</sup> 4-oxidoreductase (<small>L</small>-xylulose-forming)
| Acronym = 
| Other_names = xylitol dehydrogenase
| EC_number = 1.1.1.10
| CAS_number = 9028-17-5 
| IUBMB_EC_number = 1/1/1/10 
| GO_code =  
| image = Human xylulose reductase holoenzyme.png
| width = 
| caption = 人源木酮糖还原酶[[全酶]]（[[蛋白質數據庫|PDB]] 1pr9）
}}
'''<small>L</small>-木酮糖还原酶'''（{{lang-en|<small>L</small>-xylulose reductase}}，[[EC编号|EC]] [http://enzyme.expasy.org/EC/1.1.1.10 1.1.1.10] {{Wayback|url=http://enzyme.expasy.org/EC/1.1.1.10 |date=20201030000034 }}）是一种以[[烟酰胺腺嘌呤二核苷酸|NAD<sup>+</sup>]]或[[烟酰胺腺嘌呤二核苷酸磷酸|NADP<sup>+</sup>]]为[[受体 (生物化学)|受体]]、作用于[[供体]][[次甲基|CH]]-[[羟基|OH]][[基团]]上的[[氧化还原酶]]。这种[[酶]]能[[催化]]以下[[酶促反应]]：

:[[木糖醇]] + [[烟酰胺腺嘌呤二核苷酸磷酸|NADP<sup>+</sup>]] <math>\rightleftharpoons</math> [[L-木酮糖|<small>L</small>-木酮糖]] + NADPH + [[氢离子|H<sup>+</sup>]]

良性<small>L</small>-木酮糖还原酶缺乏可导致[[戊糖尿病]]。

== 参考文献 ==
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{{reflist}}
* {{cite journal | author = Doten, R.C. and Mortlock, R.P. | title = Characterization of xylitol-utilizing mutants of ''Erwinia uredovora''. | url = https://archive.org/details/sim_journal-of-bacteriology_1985-02_161_2/page/529 | journal = J. Bacteriol. | volume = 161 | year = 1985 | pages = 529-533 | PMID = 2981816 | language = en}}
* {{cite journal | author = Hickman, J. and Ashwell, G. A | title = sensitive and stereospecific enzymatic assay for xylulose. | url = https://archive.org/details/sim_journal-of-biological-chemistry_1959-04_234_4/page/758 | journal = J. Biol. Chem. | volume = 234 | year = 1959 | pages = 758-761 | language = en}}
* {{cite journal | author = Hollmann, S. and Touster, O. | title = The <small>L</small>-xylulose-xylitol enzyme and other polyol dehydrogenases of guinea pig liver mitochondria. | journal = J. Biol. Chem. | volume = 225 | year = 1957 | pages = 87-102| language = en}}
* {{cite journal | author = Touster, O., Reynolds, V.H. and Hutcheson, R.M. | title = The reduction of <small>L</small>-xylulose to xylitol by guinea pig liver mitochondria. | journal = J. Biol. Chem. | volume = 221 | year = 1956 | pages = 697-709 | language = en}}
{{refend}}

{{EC 1.1}}
{{蛋白聚糖代謝酶}}

[[Category:EC 1.1.1]]
[[Category:NADPH依赖性酶]]
[[Category:已知结构的酶]]