查看“︁D-苏醛糖1-脱氢酶”︁的源代码

{{DISPLAYTITLE:<small>D</small>-苏醛糖1-脱氢酶}}
{{enzyme
| Name = <small>D</small>-苏醛糖1-脱氢酶
| Systematic_name = <small>D</small>-''threo''-aldose:NAD<sup>+</sup> 1-oxidoreductase
| Acronym = 
| Other_names = <small>L</small>-fucose dehydrogenase; (2''S'',3''R'')-aldose dehydrogenase; dehydrogenase, <small>L</small>-fucose; <small>L</small>-fucose (<small>D</small>-arabinose) dehydrogenase
| EC_number = 1.1.1.122
| CAS_number = 9082-70-6
| IUBMB_EC_number = 1/1/1/122
| GO_code = 0047834
| image = 
| width = 
| caption = 
}}
'''<small>D</small>-苏醛糖1-脱氢酶'''（{{lang-en|<small>D</small>-''threo''-aldose 1-dehydrogenase }}，[[EC编号|EC]] [http://enzyme.expasy.org/EC/1.1.1.122 1.1.1.122]{{Wayback|url=http://enzyme.expasy.org/EC/1.1.1.122 |date=20120729115953 }}），是一种以[[烟酰胺腺嘌呤二核苷酸|NAD<sup>+</sup>]]或[[烟酰胺腺嘌呤二核苷酸磷酸|NADP<sup>+</sup>]]为[[受体 (生物化学)|受体]]、作用于[[供体]][[次甲基|CH]]-[[羟基|OH]][[基团]]上的[[氧化还原酶]]。这种[[酶]]能[[催化]]以下[[酶促反应]]：

:[[D-苏醛糖|<small>D</small>-苏醛糖]] + [[烟酰胺腺嘌呤二核苷酸|NAD<sup>+</sup>]] <math>\rightleftharpoons</math> <small>D</small>-苏醛糖酸-1,5-内酯 + NADH + [[氢离子|H<sup>+</sup>]]

<small>D</small>-苏醛糖1-脱氢酶也能催化[[L-岩藻糖|<small>L</small>-岩藻糖]]、[[D-阿拉伯糖|<small>D</small>-阿拉伯糖]]、[[L-木糖|<small>L</small>-木糖]]等发生反应，[[石竹假单胞菌]]（''Pseudomonas caryophylli''）和[[动物]]的<small>D</small>-苏醛糖1-脱氢酶和还分别表现出对[[L-葡萄糖|<small>L</small>-葡萄糖]]和[[L-阿拉伯糖|<small>L</small>-阿拉伯糖]]的活性，并可能受到[[对氯汞基苯甲酸]]、[[对羟基汞基苯甲酸]]、[[N-乙基顺丁烯二酰亚胺]]等[[有机物质]]或[[二价铜离子|Cu<sup>2+</sup>]]、[[二价汞离子|Hg<sup>2+</sup>]]等[[阳离子]]的抑制。<ref>{{cite journal | author = Itoh, H.; Miyoshi, T.; Yoshino, A.; Shiragami, K.; Izumori, K. | date = 1994 | title = Purification and characterization of <small>L</small>-fucose dehydrogenase from ''Agrobacterium tumefaciens'' K-28 | journal = J. Ferment. Bioeng. | volume = 77 | pages = 100-102 | doi = 10.1016/0922-338X(94)90218-6 | issue = 1 | url = http://www.sciencedirect.com/science/article/pii/0922338X94902186 }}</ref><ref>{{cite journal | author = Schacter, H.; Sarney, J.; McGuire, E.J.; Roseman, S. | date = 1969 | title = Isolation of diphosphopyridine nucleotide-dependent <small>L</small>-fucose dehydrogenase from pork liver | journal = J. Biol. Chem. | volume = 244 | pages = 4785-4792 | pmid = 4309152 | issue = 17 | url = http://www.ncbi.nlm.nih.gov/pubmed/4309152 | access-date = 2013-07-16 | archive-date = 2019-02-15 | archive-url = https://web.archive.org/web/20190215205713/https://www.ncbi.nlm.nih.gov/pubmed/4309152 | dead-url = no }}</ref><ref>{{cite journal | author = Tsuji, Y.; Koike, A.; Yamamoto, K.; Tochikura, T. | date = 1992 | title = Purification and some properties of <small>L</small>-fucose dehydrogenase from ''Agrobacterium radiobacter'' and its application to the assay of bound-fucose in glycoconjugates | journal = Biochim. Biophys. Acta. | volume = 1117 | pages = 167-173 | pmid = 1525177 | issue = 2 | url = http://www.ncbi.nlm.nih.gov/pubmed/1525177 | access-date = 2013-07-16 | archive-date = 2019-02-15 | archive-url = https://web.archive.org/web/20190215205714/https://www.ncbi.nlm.nih.gov/pubmed/1525177 | dead-url = no }}</ref>

== 参考文献 ==
{{reflist}}
{{refbegin}}
* {{cite journal | author = Sasajima KI, Sinskey AJ | date = 1979 | title = Oxidation of L-glucose by a Pseudomonad | journal = Biochim. Biophys. Acta.  | volume = 571 | pages = 120–6  | pmid = 40609 | issue = 1 }}
* {{cite journal | author = Schachter H, Sarney J, McGuire EJ, Roseman S | date = 1969 | title = Isolation of diphosphopyridine nucleotide-dependent L-fucose dehydrogenase from pork liver | journal = J. Biol. Chem.  | volume = 244 | pages = 4785–92  | pmid = 4309152 | issue = 17 }}

{{EC 1.1}}

[[Category:EC 1.1.1]]
[[Category:NADH依赖性酶]]
[[Category:未知结构的酶]]