查看“︁3-羟酰辅酶A脱氢酶”︁的源代码

{{enzyme
| Name = 3-羟酰辅酶A脱氢酶
| Systematic_name = (''S'')-3-hydroxyacyl-CoA:NAD<sup>+</sup> oxidoreductase
| Acronym = 
| Other_names = β-hydroxyacyl dehydrogenase; β-keto-reductase; 3-keto reductase; 3-hydroxyacyl coenzyme A dehydrogenase; β-hydroxyacyl-coenzyme A synthetase; β-hydroxyacylcoenzyme A dehydrogenase; β-hydroxybutyrylcoenzyme A dehydrogenase; 3-hydroxyacetyl-coenzyme A dehydrogenase; L-3-hydroxyacyl coenzyme A dehydrogenase; L-3-hydroxyacyl CoA dehydrogenase; β-hydroxyacyl CoA dehydrogenase; 3β-hydroxyacyl coenzyme A dehydrogenase; 3-hydroxybutyryl-CoA dehydrogenase; β-ketoacyl-CoA reductase; β-hydroxy acid dehydrogenase; 3-L-hydroxyacyl-CoA dehydrogenase; 3-hydroxyisobutyryl-CoA dehydrogenase; 1-specific DPN-linked β-hydroxybutyric dehydrogenase
| EC_number = 1.1.1.35
| CAS_number = 9028-40-4 | IUBMB_EC_number = 1/1/1/35 | GO_code = 0003857 | image = PDB_3had_EBI.jpg
| width = 
| caption = 3-羟酰辅酶A脱氢酶的结构（[[蛋白质数据库|PDB]] 3had）
}}
'''3-羟酰辅酶A脱氢酶'''（{{lang-en|3-hydroxyacyl-CoA dehydrogenase}}，[[EC编号|EC]] [http://enzyme.expasy.org/EC/1.1.1.35 1.1.1.35]{{Wayback|url=http://enzyme.expasy.org/EC/1.1.1.35 |date=20201029235029 }}）是一种以[[烟酰胺腺嘌呤二核苷酸|NAD<sup>+</sup>]]或[[烟酰胺腺嘌呤二核苷酸磷酸|NADP<sup>+</sup>]]为[[受体 (生物化学)|受体]]、作用于[[供体]][[次甲基|CH]]-[[羟基|OH]][[基团]]上的[[氧化还原酶]]。这种[[酶]]能[[催化]]以下[[酶促反应]]：

:(''S'')-[[3-羟酰辅酶A]] + [[烟酰胺腺嘌呤二核苷酸|NAD<sup>+</sup>]] <math>\rightleftharpoons</math> [[3-氧酰辅酶A]] + NADH + [[氢离子|H<sup>+</sup>]]

3-羟酰辅酶A脱氢酶主要参与[[脂肪酸]]的[[代谢]]过程，如[[β-氧化]]的第三步等。

== 参考文献 ==
{{refbegin}}
{{reflist}}
* {{cite journal | author = Hillmer P and Gottschalk G | date = 1974 | title = Solubilization and partial characterisation of particulate dehydrogenases from Clostridium kluyveri | journal = Biochim. Biophys. Acta  | volume = 334 | pages = 12–23 }}
* {{cite journal | author = Lehninger AL, Greville GD | title = The enzymic oxidation of alpha- and 2-beta-hydroxybutyrate | journal = Biochim. Biophys. Acta | volume = 12 | issue = 1-2 | pages = 188–202 | year = 1953 | pmid = 13115428 | doi = 10.1016/0006-3002(53)90138-3 | url = | issn = }}* {{cite journal | author = Stern JR | title = Crystalline beta-hydroxybutyryl dehydrogenase from pig heart | journal = Biochim. Biophys. Acta | volume = 26 | issue = 2 | pages = 448–9 | pmid = 13499396 | doi = 10.1016/0006-3002(57)90040-9 | url = | issn = |date=November 1957}}
* {{cite journal | author = Wakil SJ, Green DE, Mii S and Mahler HR | title = Studies on the fatty acid oxidizing system of animal tissues. VI. beta-Hydroxyacyl coenzyme A dehydrogenase | journal = J. Biol. Chem. | volume = 207 | issue = 2 | pages = 631–8 | pmid = 13163047 | doi = | url =https://archive.org/details/sim_journal-of-biological-chemistry_1954-04_207_2/page/631| issn = |date=April 1954}}
{{refend}}

{{EC 1.1}}

[[Category:EC 1.1.1]]
[[Category:NADH依赖性酶]]
[[Category:已知结构的酶]]