查看“︁3-羟苄基乙醇脱氢酶”︁的源代码

{{enzyme
| Name = 3-羟苄基乙醇脱氢酶
| Systematic_name = 3-hydroxybenzyl-alcohol:NADP<sup>+</sup> oxidoreductase
| Acronym = 
| Other_names = ''m''-hydroxybenzyl alcohol dehydrogenase; ''m''-hydroxybenzyl alcohol (NADP) dehydrogenase; ''m''-hydroxybenzylalcohol dehydrogenase
| EC_number = 1.1.1.97
| CAS_number = 9075-73-4
| IUBMB_EC_number = 1/1/1/97
| GO_code = 0047048
| width = 
| caption = 
}}
'''3-羟苄基乙醇脱氢酶'''（{{lang-en|3-hydroxybenzyl-alcohol dehydrogenase}}，[[EC编号|EC]] [http://enzyme.expasy.org/EC/1.1.1.97 1.1.1.97]{{Wayback|url=http://enzyme.expasy.org/EC/1.1.1.97 |date=20200812214831 }}），是一种以[[烟酰胺腺嘌呤二核苷酸|NAD<sup>+</sup>]]或[[烟酰胺腺嘌呤二核苷酸磷酸|NADP<sup>+</sup>]]为[[受体 (生物化学)|受体]]、作用于[[供体]][[次甲基|CH]]-[[羟基|OH]][[基团]]上的[[氧化还原酶]]。这种[[酶]]能[[催化]]以下[[酶促反应]]：

:3-羟苄基乙醇 + [[烟酰胺腺嘌呤二核苷酸磷酸|NADP<sup>+</sup>]] <math>\rightleftharpoons</math> 3-羟苄基乙醛 + NADPH + [[氢离子|H<sup>+</sup>]]

3-羟苄基乙醇脱氢酶主要参与[[甲苯]]和[[二甲苯]]的[[代谢]]过程。3-羟苄基乙醇脱氢酶是一种可溶的[[胞内酶]]，<ref>{{cite journal | author = Gillian Murphy, Feodor Lynen | title = Patulin Biosynthesis: The Metabolism of ''m''-Hydroxybenzyl Alcohol and m-Hydroxybenzaldehyde by Particulate Preparations from ''Penicillium patulum'' | journal = European Journal of Biochemistry | volume = 58 | issue = 2 | pages = 467–475 | doi = 10.1111/j.1432-1033.1975.tb02394.x | url = http://onlinelibrary.wiley.com/doi/10.1111/j.1432-1033.1975.tb02394.x/full |date=Oct 1975}}</ref>其[[相对分子质量]]约为120,000[[原子质量单位|D]]，最适[[pH值]]为7.6。这种酶是[[荨麻青霉菌]]（''Penicillium urticae''）在将[[水杨酸]]转化为[[棒曲霉素]]这一过程中的一个关键的酶。<ref>{{cite journal | author = Olivier Puel, Pierre Galtier and Isabelle P. Oswald | title = Biosynthesis and Toxicological Effects of Patulin | journal = Toxins | volume = 2 | issue = 4 | pages = 613-631 | year = 2001 | doi = 10.3390/toxins2040613 | url = http://www.mdpi.com/2072-6651/2/4/613 | access-date = 2012-08-05 | archive-date = 2020-11-11 | archive-url = https://web.archive.org/web/20201111161914/https://www.mdpi.com/2072-6651/2/4/613 | dead-url = no }}</ref>3-羟苄基乙醇脱氢酶可被[[碘代醋酸]]或[[焦碳酸二乙酯]]抑制。<ref>{{cite journal | author =P. I. Forrester, G. M. Gaucher | title = ''m''-Hydroxybenzyl alcohol dehydrogenase from ''Penicillium urticae'' | journal = Biochemistry | volume = 11 | issue = 6 | pages = 1108-1114 | year = 1972 | doi = 10.1021/bi00756a026 | url = http://pubs.acs.org/doi/abs/10.1021/bi00756a026 }}</ref>

== 参考文献 ==
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* {{cite journal | author = Forrester PI, Gaucher GM | date = 1972 | title = ''m''-Hydroxybenzyl alcohol dehydrogenase from ''Penicillium urticae'' | journal = Biochemistry | volume = 11 | pages = 1108-1114  | pmid = 4335290 | doi = 10.1021/bi00756a026 | issue = 6 }}
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{{EC 1.1}}

[[Category:EC 1.1.1]]
[[Category:NADPH依赖性酶]]
[[Category:未知结构的酶]]