查看“︁3-羟基丁酸脱氢酶”︁的源代码

{{enzyme
| Name = 3-羟基丁酸脱氢酶
| Systematic_name = (''R'')-3-hydroxybutanoate:NAD<sup>+</sup> oxidoreductase
| Acronym = 
| Other_names = NAD-β-hydroxybutyrate dehydrogenase; hydroxybutyrate oxidoreductase; β-hydroxybutyrate dehydrogenase; D-β-hydroxybutyrate dehydrogenase; D-3-hydroxybutyrate dehydrogenase; D-(–)-3-hydroxybutyrate dehydrogenase; β-hydroxybutyric acid dehydrogenase; 3-D-hydroxybutyrate dehydrogenase; β-hydroxybutyric dehydrogenase
| EC_number = 1.1.1.30
| CAS_number = 9028-38-0 
| IUBMB_EC_number = 1/1/1/30 
| GO_code = 0003858 
| image =
| width = 
| caption = 
}}
'''3-羟基丁酸脱氢酶'''（{{lang-en|3-hydroxybutyrate dehydrogenase}}，[[EC编号|EC]] [http://enzyme.expasy.org/EC/1.1.1.30 1.1.1.30]{{Wayback|url=http://enzyme.expasy.org/EC/1.1.1.30 |date=20201129163646 }}）也称为“'''3-羟丁酸脱氢酶'''”“'''D-3-羟基丁酸脱氢酶'''”或“'''D-3-羟丁酸脱氢酶'''”，是一种以[[烟酰胺腺嘌呤二核苷酸|NAD<sup>+</sup>]]或[[烟酰胺腺嘌呤二核苷酸磷酸|NADP<sup>+</sup>]]为[[受体 (生物化学)|受体]]、作用于[[供体]][[次甲基|CH]]-[[羟基|OH]][[基团]]上的[[氧化还原酶]]。这种[[酶]]能[[催化]]以下[[酶促反应]]：

:(''R'')-3-[[羟基丁酸]] + [[烟酰胺腺嘌呤二核苷酸|NAD<sup>+</sup>]] <math>\rightleftharpoons</math> [[乙酰乙酸]] + NADH + [[氢离子|H<sup>+</sup>]]

3-羟基丁酸脱氢酶主要参与[[酮类]][[化学物质|物质]]的[[生物合成|合成]]与[[降解]]以及[[丁酸]]的[[代谢]]过程。此外，这种酶还能氧化3-[[羟基单羧酸]]。

== 参考文献 ==
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* {{cite journal | author = Bergmeyer HU, Gawehn K, Klotzsch H, Krebs HA, Williamson DH | date = 1967 | title = Purification and properties of crystalline 3-hydroxybutyrate dehydrogenase from Rhodopseudomonas spheroides | url = https://archive.org/details/sim_biochemical-journal_1967-02_102_2/page/423 | journal = Biochem. J.  | volume = 102 | pages = 423–31  | pmid = 4291491 | issue = 2 | pmc = 1270263 }}
* {{cite journal | author = Delafield FP, Cooksey KE, Doudoroff M | date = 1965 | title = beta-Hydroxybutyric dehydrogenase and dimer hydrolase of Pseudomonas lemoignei | journal = J. Biol. Chem.  | volume = 240 | pages = 4023–8  | pmid = 4954074 | issue = 10 }}
* {{cite journal | author = Lehninger AL, Sudduth HC and Wise JB | date = 1960 | title = D-beta-Hydroxybutyric dehydrogenase of mitochondria | url = https://archive.org/details/sim_journal-of-biological-chemistry_1960-08_235_8/page/2450 | journal = J. Biol. Chem.  | volume = 235 | pages = 2450–2455 | pmid = 14415394 }}
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{{EC 1.1}}
{{膽固醇與類固醇代謝酶}}

[[Category:EC 1.1.1]]
[[Category:NADH依赖性酶]]
[[Category:已知结构的酶]]