查看“︁雌二醇17β-脱氢酶”︁的源代码

{{enzyme
| Name = 雌二醇17β-脱氢酶
| Systematic_name = estradiol-17β:NAD(P)<sup>+</sup> 17-oxidoreductase
| Acronym = 17β-HSD
| Other_names = 20α-hydroxysteroid dehydrogenase; 17β,20α-hydroxysteroid dehydrogenase; 17β-estradiol dehydrogenase; estradiol dehydrogenase; estrogen 17-oxidoreductase
| EC_number = 1.1.1.62
| CAS_number = 9028-61-9 | IUBMB_EC_number = 1/1/1/62 | GO_code = 0004303 | image =
| width = 
| caption = 
}}
'''雌二醇17β-脱氢酶'''（{{lang-en|estradiol 17β-dehydrogenase}}，[[EC编号|EC]] [http://enzyme.expasy.org/EC/1.1.1.62 1.1.1.62] {{Wayback|url=http://enzyme.expasy.org/EC/1.1.1.62 |date=20201029224911 }}）是一种以[[烟酰胺腺嘌呤二核苷酸|NAD<sup>+</sup>]]或[[烟酰胺腺嘌呤二核苷酸磷酸|NADP<sup>+</sup>]]为[[受体 (生物化学)|受体]]、作用于[[供体]][[次甲基|CH]]-[[羟基|OH]][[基团]]上的[[氧化还原酶]]。这种[[酶]]能[[催化]]以下[[酶促反应]]：

:[[雌二醇|雌二醇-17β]] + [[烟酰胺腺嘌呤二核苷酸|NAD]]([[烟酰胺腺嘌呤二核苷酸磷酸|P]])<sup>+</sup> <math>\rightleftharpoons</math> [[雌酮]] + NAD(P)H + [[氢离子|H<sup>+</sup>]]

雌二醇17β-脱氢酶主要参与[[雄激素]]和[[雌激素]][[代谢]]过程。

== 参考文献 ==
{{reflist}}
{{refbegin}}
* {{cite journal | author = Kautsky MP, Hagerman DD | date = 1970 | title = 17 Beta-estradiol dehydrogenase of ovine ovaries | journal = J. Biol. Chem.  | volume = 245 | pages = 1978–84  | pmid = 4314937 | issue = 8 }}{{wordbreak}}* {{cite journal | author = LANGER LJ, ALEXANDER JA, ENGEL LL | date = 1959 | title = Human placental estradiol-17 beta dehydrogenase. II. Kinetics and substrate specificities | url = https://archive.org/details/sim_journal-of-biological-chemistry_1959-10_234_10/page/2609 | journal = J. Biol. Chem.  | volume = 234 | pages = 2609–14  | pmid = 14413943 }}
{{refend}}

{{EC 1.1}}

[[Category:EC 1.1.1]]
[[Category:NADH依赖性酶]]
[[Category:NADPH依赖性酶]]
[[Category:已知结构的酶]]