查看“︁酰基甘油酮磷酸还原酶”︁的源代码

{{enzyme
| Name = 酰基甘油酮磷酸还原酶
| Systematic_name = 1-palmitoylglycerol-3-phosphate:NADP<sup>+</sup> oxidoreductase
| Acronym = 
| Other_names = acyl/alkyl dihydroxyacetone phosphate reductase; palmitoyldihydroxyacetone-phosphate reductase; palmitoyl dihydroxyacetone phosphate reductase; palmitoyl-dihydroxyacetone-phosphate reductase; acyldihydroxyacetone phosphate reductase; palmitoyl dihydroxyacetone phosphate reductase
| EC_number = 1.1.1.101
| CAS_number = 37250-35-4
| IUBMB_EC_number = 1/1/1/101
| GO_code = 0000140
| image = 
| width = 
| caption = 
}}
'''酰基甘油酮磷酸还原酶'''（{{lang-en|acylglycerone-phosphate reductase}}，[[EC编号|EC]] [http://enzyme.expasy.org/EC/1.1.1.101 1.1.1.101] {{Wayback|url=http://enzyme.expasy.org/EC/1.1.1.101 |date=20190505113237 }}），是一种以[[烟酰胺腺嘌呤二核苷酸|NAD<sup>+</sup>]]或[[烟酰胺腺嘌呤二核苷酸磷酸|NADP<sup>+</sup>]]为[[受体 (生物化学)|受体]]、作用于[[供体]][[次甲基|CH]]-[[羟基|OH]][[基团]]上的[[氧化还原酶]]。这种[[酶]]能[[催化]]以下[[酶促反应]]：

:1-[[棕榈酸甘油]]3-[[磷酸]] + [[烟酰胺腺嘌呤二核苷酸磷酸|NADP]]<sup>+</sup> <math>\rightleftharpoons</math> [[棕榈酸甘油酮]]磷酸 + NADPH + [[氢离子|H<sup>+</sup>]]

酰基甘油酮磷酸还原酶主要参与[[甘油磷脂]]和[[醚酯]]（ether lipid）的[[代谢]]过程。这种酶也能作用于[[烷基甘油酮]]3-磷酸和[[烷基甘油]]3-磷酸。对[[啮齿类动物]][[肝脏]][[细胞]]的研究表明，这种酶大约有三分之二位于细胞的[[过氧化物酶体]]，其余位于[[微粒体]]。<ref>{{cite journal | author = Ghosh MK, Hajra AK | title = Subcellular distribution and properties of acyl/alkyl dihydroxyacetone phosphate reductase in rodent livers. | journal = Arch Biochem Biophys | volume = 245 | issue = 2 | pages = 523-530 | pmid = 3954368 | url = http://www.ncbi.nlm.nih.gov/pubmed/3954368 | date = Mar 1986 | access-date = 2012-08-08 | archive-date = 2016-06-03 | archive-url = https://web.archive.org/web/20160603012614/http://www.ncbi.nlm.nih.gov/pubmed/3954368 }}</ref>酰基甘油酮磷酸还原酶仅能在高[[离子强度]]的[[溶液]]中、在NADPH存在下由[[洗涤剂]][[溶解]]。<ref>{{cite journal | author = Datta SC, Ghosh MK, Hajra AK | title = Purification and properties of acyl/alkyl dihydroxyacetone-phosphate reductase from guinea pig liver peroxisomes. | journal = J Biol Chem. | volume = 265 | issue = 14 | pages = 8268-8274 | pmid = 2335525 | url = http://www.ncbi.nlm.nih.gov/pubmed/2335525 | date = May 15, 1990 | access-date = 2012-08-08 | archive-date = 2019-06-14 | archive-url = https://web.archive.org/web/20190614072920/https://www.ncbi.nlm.nih.gov/pubmed/2335525 | dead-url = no }}</ref>

== 参考文献 ==
{{reflist}}
{{refbegin}}
* {{cite journal | author = LaBelle EF Jr, Hajra AK | date = 1972 | title = Enzymatic reduction of alkyl and acyl derivatives of dihydroxyacetone phosphate by reduced pyridine nucleotides | journal = J. Biol. Chem.  | volume = 247 | pages = 5825–34  | pmid = 4403490 | issue = 18 }}
{{refend}}

{{EC 1.1}}

[[Category:EC 1.1.1]]
[[Category:NADPH依赖性酶]]
[[Category:未知结构的酶]]