查看“︁苹果酸脱氢酶 (草酰乙酸脱羧) (NADP+)”︁的源代码

{{DISPLAYTITLE:苹果酸脱氢酶 (草酰乙酸脱羧) (NADP<sup>+</sup>)}}
{{enzyme
| Name = 苹果酸脱氢酶 (草酰乙酸脱羧) (NADP<sup>+</sup>)
| Systematic_name = (''S'')-malate:NADP<sup>+</sup> oxidoreductase (oxaloacetate-decarboxylating)
| Acronym = 
| Other_names = 'malic' enzyme; pyruvic-malic carboxylase; malate dehydrogenase (decarboxylating, NADP); NADP-linked decarboxylating malic enzyme; NADP-malic enzyme; NADP-specific malic enzyme; NADP-specific malate dehydrogenase; malate dehydrogenase (NADP, decarboxylating); L-malate:NADP oxidoreductase; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP)
| EC_number = 1.1.1.40
| CAS_number = 9028-47-1 | IUBMB_EC_number = 1/1/1/40 | GO_code = 0004473 | image = Malic-enzyme 2AW5.png
| width = 
| caption = 苹果酸脱氢酶 (草酰乙酸脱羧) (NADP<sup>+</sup>)的结构（[[蛋白质数据库|PDB]] 2AW5）
}}
'''苹果酸脱氢酶 (草酰乙酸脱羧) (NADP<sup>+</sup>)'''（{{lang-en|malate dehydrogenase (oxaloacetate-decarboxylating) (NADP<sup>+</sup>)}}，[[EC编号|EC]] [http://enzyme.expasy.org/EC/1.1.1.40 1.1.1.40] {{Wayback|url=http://enzyme.expasy.org/EC/1.1.1.40 |date=20201129085023 }}）是一种以[[烟酰胺腺嘌呤二核苷酸|NAD<sup>+</sup>]]或[[烟酰胺腺嘌呤二核苷酸磷酸|NADP<sup>+</sup>]]为[[受体 (生物化学)|受体]]、作用于[[供体]][[次甲基|CH]]-[[羟基|OH]][[基团]]上的[[氧化还原酶]]。这种[[酶]]能[[催化]]以下[[酶促反应]]：

:(''S'')-[[苹果酸]] + [[烟酰胺腺嘌呤二核苷酸磷酸|NADP<sup>+</sup>]] <math>\rightleftharpoons</math> [[丙酮酸]] + [[二氧化碳|CO<sub>2</sub>]] + NADPH

苹果酸脱氢酶 (草酰乙酸脱羧) (NADP<sup>+</sup>)是[[C4类二氧化碳固定|C<sub>4</sub>]]和[[景天酸代谢|CAM]][[植物]]固定[[二氧化碳]]过程中使用的三种脱羧酶之一（其余两种分别为[[苹果酸脱氢酶 (脱羧)]]和[[磷酸烯醇丙酮酸羧化激酶]]）。<ref>{{cite book |editor=Sage RF, Monson RK |author=Kanai R, Edwards, GE |title=C4 PlantBiology |url=https://archive.org/details/cplantbiology0000unse |year=1999 |pages=[https://archive.org/details/cplantbiology0000unse/page/43 43]-87 |chapter=3. The Biochemistry of C4 Photosynthesis |isbn=0126144400}}</ref><ref>{{cite journal |author=Christopher JT, Holtum JAM |year=1996 |title=Patterns of carbon partitioning in leaves of Crassulacean acid metabolism species during deacidification |url=https://archive.org/details/sim_plant-physiology_1996-09_112_1/page/393 |journal=Plant Physiol. |volume=112 |issue=1 |pages=393-399 |pmid=12226397 |pmc=157961}}</ref>

== 参考文献 ==
{{reflist}}
{{refbegin}}
* {{cite journal | author = Harary, I., Korey, S.R. and Ochoa, S. | date = 1953 | title = Biosynthesis of dicarboxylic acids by carbon dioxide fixation. VII Equilibrium of malic enzyme reaction | journal = J. Biol. Chem. | volume = 203 | pages = 595-604 | pmid = 13084629 | issue = 2 }}
* {{cite journal | author = Ochoa S, Mehler AH and Kornberg A | date = 1948 | title = Biosynthesis of dicarboxylic acids by carbon dioxide fixation. I Isolation and properties of an enzyme from pigeon liver catalyzing the reversible oxidative decarboxylation of l-malic acid | url = https://archive.org/details/sim_journal-of-biological-chemistry_1948-07_174_3/page/979 | journal = J. Biol. Chem.  | volume = 174 | pages = 979-1000 }}
* {{cite journal | author = RUTTER WJ, LARDY HA | date = 1958 | title = Purification and properties of pigeon liver malic enzyme | url = https://archive.org/details/sim_journal-of-biological-chemistry_1958-08_233_2/page/374 | journal = J. Biol. Chem.  | volume = 233 | pages = 374–82  | pmid = 13563505 | issue = 2 }}
* {{cite journal | author = Strickland RG | date = 1959 | title = Some properties of the malic enzyme of pigeon liver. 1. Conversion of malate into pyruvate | url = https://archive.org/details/sim_biochemical-journal_1959-12_73_4/page/646 | journal = Biochem. J. | volume = 73 | pages = 646-654 }}
* {{cite journal | author = Strickland RG | date = 1959 | title = Some properties of the malic enzyme of pigeon liver. 2. Synthesis of malate from pyruvate | url = https://archive.org/details/sim_biochemical-journal_1959-12_73_4/page/654 | journal = Biochem. J. | volume = 73 | pages = 654–659 | pmid=13834657 | pmc=1197116}}
* {{cite journal | author = Walker DA | date = 1960 | title = Physiological studies on acid metabolism. 7. Malic enzyme from Kalanchoe crenata: effects of carbon dioxide concentration | url = https://archive.org/details/sim_biochemical-journal_1960-02_74_2/page/216 | journal = Biochem. J.  | volume = 74 | pages = 216-223 | pmid=13842495 | pmc=1204145}}
{{refend}}

{{EC 1.1}}

[[Category:EC 1.1.1]]
[[Category:NADPH依赖性酶]]
[[Category:已知结构的酶]]