查看“︁苹果酸脱氢酶 (脱羧)”︁的源代码

{{enzyme
| Name = 苹果酸脱氢酶 (脱羧)
| Systematic_name = (''S'')-malate:NAD<sup>+</sup> oxidoreductase (decarboxylating)
| Acronym = 
| Other_names = 'malic' enzyme; pyruvic-malic carboxylase; NAD-specific malic enzyme; NAD-malic enzyme
| EC_number = 1.1.1.39
| CAS_number = 9028-46-0 | IUBMB_EC_number = 1/1/1/39 | GO_code = 0004471 | image = 1efk.jpg
| width = 270
| caption = 
}}
'''苹果酸脱氢酶 (脱羧)'''（{{lang-en|malate dehydrogenase (decarboxylating)}}，[[EC编号|EC]] [http://enzyme.expasy.org/EC/1.1.1.39 1.1.1.39] {{Wayback|url=http://enzyme.expasy.org/EC/1.1.1.39 |date=20191220020900 }}）是一种以[[烟酰胺腺嘌呤二核苷酸|NAD<sup>+</sup>]]或[[烟酰胺腺嘌呤二核苷酸磷酸|NADP<sup>+</sup>]]为[[受体 (生物化学)|受体]]、作用于[[供体]][[次甲基|CH]]-[[羟基|OH]][[基团]]上的[[氧化还原酶]]。这种[[酶]]能[[催化]]以下[[酶促反应]]：

:(''S'')-[[苹果酸]] + [[烟酰胺腺嘌呤二核苷酸|NAD<sup>+</sup>]] <math>\rightleftharpoons</math> [[丙酮酸]] + [[二氧化碳|CO<sub>2</sub>]] + NADH

苹果酸脱氢酶 (脱羧)主要参与丙酮酸的[[代谢]]过程以及[[固碳作用]]（Carbon fixation）。苹果酸脱氢酶 (脱羧)是[[C4类二氧化碳固定|C<sub>4</sub>]]和[[景天酸代谢|CAM]][[植物]]固定[[二氧化碳]]过程中使用的三种脱羧酶之一（其余两种分别为[[苹果酸脱氢酶 (草酰乙酸脱羧) (NADP+)|苹果酸脱氢酶 (草酰乙酸脱羧) (NADP<sup>+</sup>)]][[磷酸烯醇丙酮酸羧化激酶]]）。<ref>{{cite book |editor=Sage RF, Monson RK |author=Kanai R, Edwards, GE |title=C4 Plant Biology |url=https://archive.org/details/cplantbiology0000unse |year=1999 |pages=[https://archive.org/details/cplantbiology0000unse/page/43 43]-87 |chapter=3. The Biochemistry of C4 Photosynthesis |isbn=0126144400}}</ref><ref>{{cite journal |author=Christopher JT, Holtum JAM |year=1996 |title=Patterns of carbon partitioning in leaves of Crassulacean acid metabolism species during deacidification |url=https://archive.org/details/sim_plant-physiology_1996-09_112_1/page/393 |journal=Plant Physiol. |volume=112 |issue=1 |pages=393-399 |pmid=12226397 |pmc=157961}}</ref>

== 参考文献 ==
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{{reflist}}
* {{cite journal | author = Saz HJ and Hubbard JA | date = 1957 | title = The oxidative decarboxylation of malate by Ascaris lumbricoides | journal = J. Biol. Chem.  | volume = 225 | pages = 921–933 | pmid=13416294}}
{{refend}}

{{EC 1.1}}

[[Category:EC 1.1.1]]
[[Category:NADH依赖性酶]]
[[Category:已知结构的酶]]