查看“︁甘油-3-磷酸脱氢酶 (NAD+)”︁的源代码

{{DISPLAYTITLE:甘油-3-磷酸脱氢酶 (NAD<sup>+</sup>)}}
{{enzyme
| Name = 甘油-3-磷酸脱氢酶 (NAD<sup>+</sup>)
| Systematic_name = ''sn''-glycerol-3-phosphate:NAD<sup>+</sup> 2-oxidoreductase
| Acronym = GPD
| Other_names = α-glycerol phosphate dehydrogenase (NAD); α-glycerophosphate dehydrogenase (NAD); glycerol 1-phosphate dehydrogenase; glycerol phosphate dehydrogenase (NAD); glycerophosphate dehydrogenase (NAD); hydroglycerophosphate dehydrogenase; L-α-glycerol phosphate dehydrogenase; L-α-glycerophosphate dehydrogenase; L-glycerol phosphate dehydrogenase; L-glycerophosphate dehydrogenase; NAD-α-glycerophosphate dehydrogenase; NAD-dependent glycerol phosphate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase; NAD-L-glycerol-3-phosphate dehydrogenase; NAD-linked glycerol 3-phosphate dehydrogenase; NADH-dihydroxyacetone phosphate reductase; glycerol-3-phosphate dehydrogenase (NAD)
| EC_number = 1.1.1.8
| CAS_number = 9075-65-4 | IUBMB_EC_number = 1/1/1/8 | GO_code = 0004367 | image = Glycerol-3-phosphate dehydrogenase 1.png
| width = 
| caption = 人源甘油-3-磷酸脱氢酶1（[[蛋白质数据库|PDB]] 1x0v）
}}
'''甘油-3-磷酸脱氢酶 (NAD<sup>+</sup>)'''（{{lang-en|glycerol-3-phosphate dehydrogenase (NAD<sup>+</sup>)}}，[[EC编号|EC]] [http://enzyme.expasy.org/EC/1.1.1.8 1.1.1.8] {{Wayback|url=http://enzyme.expasy.org/EC/1.1.1.8 |date=20201129170733 }}）是一种以[[烟酰胺腺嘌呤二核苷酸|NAD<sup>+</sup>]]或[[烟酰胺腺嘌呤二核苷酸磷酸|NADP<sup>+</sup>]]为[[受体 (生物化学)|受体]]、作用于[[供体]][[次甲基|CH]]-[[羟基|OH]][[基团]]上的[[氧化还原酶]]。这种[[酶]]能[[催化]]以下[[酶促反应]]：

:[[立体专一序数|''sn'']]-[[甘油]]-3-[[磷酸]] + [[烟酰胺腺嘌呤二核苷酸|NAD<sup>+</sup>]] <math>\rightleftharpoons</math> [[磷酸甘油酮]] + NADH + [[氢离子|H<sup>+</sup>]]

<center>[[File:Dihydroxyacetone phosphate to glycerol 3-phosphate en.svg|400px]]</center>{{Wordbreak}}甘油-3-磷酸脱氢酶 (NAD<sup>+</sup>)主要参与[[甘油磷酸脂]]的[[代谢]]过程。

== 参考文献 ==
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{{reflist}}
* {{cite book | author = Boyer, P.D., Lardy, H. and Myrback, K. (Eds.) | title = The Enzymes | edition = 2nd | volume = 7 | publisher = Academic Press | location= New York | year = 1963 | pages = 85-96 }}{{Wordbreak}}* {{cite journal | author = Brosemer RW, Kuhn RW | year = 1969 | title = Comparative structural properties of honeybee and rabbit alpha-glycerophosphate dehydrogenases | journal = Biochemistry.  | volume = 8 | pages = 2095–105  | pmid = 4307630 | doi = 10.1021/bi00833a047 | issue = 5 }}{{Wordbreak}}* {{cite journal | author = O'Brien SJ, MacIntyre RJ | year = 1972 | title = The  -glycerophosphate cycle in Drosophila melanogaster. I Biochemical and developmental aspects | journal = Biochem. Genet.  | volume = 7 | pages = 141–61  | pmid = 4340553 | doi = 10.1007/BF00486085 | issue = 2 }}{{Wordbreak}}* {{cite journal | author = Warkentin DL, Fondy TP | year = 1973 | title = Isolation and characterization of cytoplasmic L-glycerol-3-phosphate dehydrogenase from rabbit-renal-adipose tissue and its comparison with the skeletal-muscle enzyme | journal = Eur. J. Biochem.  | volume = 36 | pages = 97–109  | pmid = 4200180 | doi = 10.1111/j.1432-1033.1973.tb02889.x | issue = 1 }}{{Wordbreak}}* {{cite journal | author = Albertyn J, van Tonder A, Prior BA | year = 1992 | title = Purification and characterization of glycerol-3-phosphate dehydrogenase of Saccharomyces cerevisiae | url = https://archive.org/details/sim_febs-letters_1992-08-17_308_2/page/n23 | journal = FEBS. Lett.  | volume = 308 | pages = 130–2  | pmid = 1499720 | doi = 10.1016/0014-5793(92)81259-O | issue = 2 }}{{Wordbreak}}* {{cite journal | author = Koekemoer TC, Litthauer D, Oelofsen W | year = 1995 | title = Isolation and characterization of adipose tissue glycerol-3-phosphate dehydrogenase | url = https://archive.org/details/sim_international-journal-of-biochemistry-cell-biology_1995-06_27_6/page/625 | journal = Int. J. Biochem. Cell. Biol.  | volume = 27 | pages = 625–32  | pmid = 7671141 | doi = 10.1016/1357-2725(95)00012-E | issue = 6 }}
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{{EC 1.1}}

[[Category:EC 1.1.1]]
[[Category:NADH依赖性酶]]
[[Category:已知结构的酶]]