查看“︁甘油-3-磷酸脱氢酶 (NAD(P)+)”︁的源代码

{{DISPLAYTITLE:甘油-3-磷酸脱氢酶 [NAD(P)<sup>+</sup>]}}
{{enzyme
| Name = 甘油-3-磷酸脱氢酶 [NAD(P)<sup>+</sup>]
| Systematic_name = ''sn''-glycerol-3-phosphate:NAD(P)<sup>+</sup> 2-oxidoreductase
| Acronym = 
| Other_names = L-glycerol-3-phosphate:NAD(P) oxidoreductase; glycerol phosphate dehydrogenase (nicotinamide adenine dinucleotide (phosphate)); glycerol 3-phosphate dehydrogenase (NADP); glycerol-3-phosphate dehydrogenase [NAD(P)]
| EC_number = 1.1.1.94
| CAS_number = 37250-30-9
| IUBMB_EC_number = 1/1/1/94
| GO_code = 0047952
| image = 
| width = 
| caption = 
}}
'''甘油-3-磷酸脱氢酶 [NAD(P)<sup>+</sup>]'''（{{lang-en|glycerol-3-phosphate dehydrogenase [NAD(P)<sup>+</sup>]}}，[[EC编号|EC]] [http://enzyme.expasy.org/EC/1.1.1.94 1.1.1.94] {{Wayback|url=http://enzyme.expasy.org/EC/1.1.1.94 |date=20210422000636 }}），是一种以[[烟酰胺腺嘌呤二核苷酸|NAD<sup>+</sup>]]或[[烟酰胺腺嘌呤二核苷酸磷酸|NADP<sup>+</sup>]]为[[受体 (生物化学)|受体]]、作用于[[供体]][[次甲基|CH]]-[[羟基|OH]][[基团]]上的[[氧化还原酶]]。这种[[酶]]能[[催化]]以下[[酶促反应]]：

:[[立体专一序数|''sn'']]-[[甘油磷酸|甘油-3-磷酸]] + [[烟酰胺腺嘌呤二核苷酸|NAD]]([[烟酰胺腺嘌呤二核苷酸磷酸|P]])<sup>+</sup> <math>\rightleftharpoons</math> [[磷酸甘油酮]] + NAD(P)H + [[氢离子|H<sup>+</sup>]]

甘油-3-磷酸脱氢酶 [NAD(P)<sup>+</sup>]主要参与[[磷酸甘油酯]]的[[代谢]]过程。[[大肠杆菌]]（''Escherichia coli''）的甘油-3-磷酸脱氢酶 [NAD(P)<sup>+</sup>]显示出对NADPH的B域的特异性。

== 参考文献 ==
{{reflist}}
{{refbegin}}
* {{cite journal | author = Kito M, Pizer LI | date = 1969 | title = Purification and regulatory properties of the biosynthetic L-glycerol 3-phosphate dehydrogenase from ''Escherichia coli'' | journal = J. Biol. Chem.  | volume = 244 | pages = 3316-3323  | pmid = 4389388 | issue = 12 }}
* {{cite journal | author = Edgar JR, Bell RM | date = 1978 | title = Biosynthesis in Escherichia coli fo ''sn''-glycerol 3-phosphate, a precursor of phospholipid | journal = J. Biol. Chem.  | volume = 253 | pages = 6348-6353  | pmid = 355254 | issue = 18 }}
* {{cite journal | author = Edgar JR, Bell RM | date = 1978 | title = Biosynthesis in Escherichia coli of sn-glycerol 3-phosphate, a precursor of phospholipid. Kinetic characterization of wild type and feedback-resistant forms of the biosynthetic ''sn''-glycerol-3-phosphate dehydrogenase | journal = J. Biol. Chem.  | volume = 253 | pages = 6354-6363  | pmid = 28326 | issue = 18 }}
* {{cite journal | author = Edgar JR, Bell RM | date = 1980 | title = Biosynthesis in ''Escherichia coli'' of ''sn''-glycerol-3-phosphate, a precursor of phospholipid. Further kinetic characterization of wild type and feedback-resistant forms of the biosynthetic ''sn''-glycerol-3-phosphate dehydrogenase | journal = J. Biol. Chem.  | volume = 255 | pages = 3492-3497  | pmid = 6767719 | issue = 8 }}{{refend}}

{{EC 1.1}}

[[Category:EC 1.1.1]]
[[Category:NADH依赖性酶]]
[[Category:NADPH依赖性酶]]
[[Category:未知结构的酶]]