查看“︁尿苷二磷酸-葡萄糖6-脱氢酶”︁的源代码

{{enzyme
| Name = 尿苷二磷酸-葡萄糖6-脱氢酶
| Systematic_name = UDP-glucose:NAD<sup>+</sup> 6-oxidoreductase
| Acronym = 
| Other_names = UDP-glucose dehydrogenase; uridine diphosphoglucose dehydrogenase; UDPG dehydrogenase; UDPG:NAD oxidoreductase; UDP-α-D-glucose:NAD oxidoreductase; UDPglucose:NAD<sup>+</sup> oxidoreductase; uridine diphosphate glucose dehydrogenase; UDP-D-glucose dehydrogenase; uridine diphosphate D-glucose dehydrogenase
| EC_number = 1.1.1.22
| CAS_number = 9028-26-6 | IUBMB_EC_number = 1/1/1/22 | GO_code = 0003979 
| image = 2qg4.jpg
| width = 270
| caption = 
}}
'''尿苷二磷酸-葡萄糖6-脱氢酶'''（{{lang-en|UDP-glucose 6-dehydrogenase}}，[[EC编号|EC]] [http://enzyme.expasy.org/EC/1.1.1.22 1.1.1.22] {{Wayback|url=http://enzyme.expasy.org/EC/1.1.1.22 |date=20120412133851 }}）是一种以[[烟酰胺腺嘌呤二核苷酸|NAD<sup>+</sup>]]或[[烟酰胺腺嘌呤二核苷酸磷酸|NADP<sup>+</sup>]]为[[受体 (生物化学)|受体]]、作用于[[供体]][[次甲基|CH]]-[[羟基|OH]][[基团]]上的[[氧化还原酶]]。这种[[酶]]能[[催化]]以下[[酶促反应]]：

:[[尿苷二磷酸]]-[[葡萄糖]] + 2 [[烟酰胺腺嘌呤二核苷酸|NAD<sup>+</sup>]] + [[水|H<sub>2</sub>O]] <math>\rightleftharpoons</math> 尿苷二磷酸-[[葡糖醛酸]] + 2 NADH + 2 H<sup>+</sup>

尿苷二磷酸-葡萄糖6-脱氢酶主要参与4种代谢途径，包括：[[戊糖]]和[[葡萄糖醛酸]]之间的转化、[[抗坏血酸]]和[[醛糖二酸]]的[[代谢]]、[[淀粉]]和[[蔗糖]]之间的转化以及[[核苷酸糖]]的代谢过程。

== 参考文献 ==
{{refbegin}}
{{reflist}}
* {{cite journal | author = Bauer S | date = 1975 | title = Uridine diphosphate 2-deoxyglucose. Chemical synthesis, enzymic oxidation and epimerization | journal = Biochim. Biophys. Acta.  | volume = 381 | pages = 301–7  | pmid = 1091296 | last2 = Kusov | first2 = YY | last3 = Shibaev | first3 = VN | last4 = Kochetkov | first4 = NK | last5 = Bielý | first5 = P | last6 = Kucár | first6 = S | last7 = Bauer | first7 = S | issue = 2 }}{{Wordbreak}}* {{cite journal | author = Maxwell, E.S., Kalckar, H.M. and Strominger, J.L. | date = 1956 | title = Some properties of uridine diphosphoglucose dehydrogenase | journal = Arch. Biochem. Biophys.  | volume = 65 | pages = 2–10  | pmid = 13373402 | doi = 10.1016/0003-9861(56)90171-0 | issue = 1 }}{{Wordbreak}}* {{cite journal | author = Strominger, J.L. and Mapson, L.W. | date = 1957 | title = Uridine diphosphoglucose dehydrogenase of pea seedlings | url = https://archive.org/details/sim_biochemical-journal_1957-08_66_4/page/567 | journal = Biochem. J.  | volume = 66 | pages = 567–72  | pmid = 13459898 | issue = 4 | pmc = 1200063 }}{{Wordbreak}}* {{cite journal | author = Strominger, J.L., Maxwell, E.S., Axelrod, J. and Kalckar, H.M. | date = 1957 | title = Enzymatic formation of uridine diphosphoglucuronic acid | journal = J. Biol. Chem.  | volume = 224 | pages = 79–90  | pmid = 13398389 | issue = 1 }}
{{refend}}

{{EC 1.1}}

[[Category:EC 1.1.1]]
[[Category:NADH依赖性酶]]
[[Category:已知结构的酶]]