查看“︁对氨基苯胂酸”︁的源代码

{{NoteTA
|G1=Chemistry
}}
{{Chembox
|   NameEn = Arsanilic acid
|   ImageFile = ArsanilicTaut.png
|   ImageSize = 350px
|   ImageName = Chemical structure of arsanilic acid
|   ImageFile1 = P-arsanilic-acid-from-xtal-3D-balls.png
|   ImageSize1 = 200px
|   ImageName1 = Ball-and-stick model of the solid-state zwitterionic structure of arsanilic acid
|   IUPACName = 4-aminophenylarsonic acid
|   IUPACNameZh = 4-氨基苯胂酸
|   OtherNames = 氨苯胂酸；对氨苯胂酸；对氨基苯砷酸；胂酸苯胺；对阿散酸；阿散酸
| Section1 = {{Chembox Identifiers
| CASNo = 98-50-0
| CASNo_Ref = {{cascite|correct|CAS}}
|  SMILES  =  
|  ChemSpiderID  =  
|  RTECS  =  
|  UNII_Ref  = {{fdacite|changed|FDA}}|  UNII  =  UDX9AKS7GM
|  DrugBank_Ref  = {{drugbankcite|correct|drugbank}}|  DrugBank  =  DB03006
|  ChEMBL_Ref  = {{ebicite|correct|EBI}}|  ChEMBL  =  351769
|  ChEBI_Ref  = {{ebicite|correct|EBI}}|  ChEBI  =  49477
|  PubChem  =  6432805
|  ChemSpiderID_Ref  = {{chemspidercite|correct|chemspider}}|  InChI  =  1/C6H8AsNO3/c8-6-3-1-5(2-4-6)7(9,10)11/h1-4H,8H2,(H2,9,10,11)
|  InChIKey  =  XKNKHVGWJDPIRJ-UHFFFAOYAQ
|  StdInChI_Ref  = {{stdinchicite|correct|chemspider}}|  StdInChI  =  1S/C6H8AsNO3/c8-6-3-1-5(2-4-6)7(9,10)11/h1-4H,8H2,(H2,9,10,11)
|  StdInChIKey_Ref  = {{stdinchicite|correct|chemspider}}|  StdInChIKey  =  XKNKHVGWJDPIRJ-UHFFFAOYSA-N
}}
| Section2 = {{Chembox Properties
|   Formula = C<sub>6</sub>H<sub>8</sub>AsNO<sub>3</sub>
|   MolarMass = 217.054 
|   Appearance = 白色固体
|   Density = 1.957 g/cm<sup>3</sup>
|   Solubility = 微溶于冷水
|   Solvent = 
|   SolubleOther = 
|   MeltingPt = 232&nbsp;°C
|   BoilingPt = 
|   pKa = 
|   Viscosity = 
  }}
| Section3 = {{Chembox Structure
|   CrystalStruct =
|   Dipole =
  }}
| Section7 = {{Chembox Hazards
|   ExternalMSDS =
|   MainHazards = 
|   EUHazardSymbol = {{Chembox EUHazardSymbol|T|N}}
|   NFPA-H = 2
|   NFPA-F = 0
|   NFPA-R = 0
|   FlashPt = 
|   RPhrases = {{R23/25}}, {{R50/53}}
|   SPhrases = {{S20/21}}, {{S28}}, {{S45}}, {{S60}}, {{S61}}
  }}
| Section8 = {{Chembox Related
|   Function = 
|   OtherFunctn = 
|   OtherCpds = [[对氨基苯膦酸]]
  }}
}}

'''对氨基苯胂酸'''，俗称'''对阿散酸'''、'''阿散酸'''（Arsanilic acid），一种[[有机砷化合物]]，是[[苯胂酸]]苯环4-位被[[氨基]]取代形成的化合物。

== 性质 ==
无色或白色针状晶体。几乎无臭。有毒。不溶于稀无机酸、[[丙酮]]、[[乙醚]]、[[氯仿]]、[[苯]]，微溶于冷水、[[乙醇]]、[[乙酸]]，溶于热水、碳酸碱溶液、浓无机酸溶液、[[戊醇]]。<ref name="chemyq">{{cite web|url=http://www.chemyq.com/xz/xz11/101312otdff.htm|title=4-氨基苯胂酸；对氨基苯砷酸；胂酸苯胺；对阿散酸；对氨基苯胂酸|publisher=化工引擎|accessdate=2009-09-06|archive-date=2019-08-15|archive-url=https://web.archive.org/web/20190815152917/http://www.chemyq.com/xz/xz11/101312otdff.htm|dead-url=no}}</ref> 主要以[[两性离子]]形式（<math>\rm \ H_3N^+C_6H_4AsO_3H^-</math>）存在。<ref>{{cite journal en| author = R. H. Nuttall and W. N. Hunter | title = ''p-Arsanilic Acid, a Redetermination | journal = [[Acta Cryst.]] | year = 1996 | volume = C52 | pages = 1681-1683 | doi = 10.1107/S010827019501657X}}</ref>

== 制取 ==
* [[Béchamp反应]]：由 Antoine Béchamp 于1859年发明。
[[苯胺]]与[[五氧化二砷]]（[[砷酸]]）反应[[胂化]]，得对氨基苯胂酸。<ref>{{OrgSynth | author = W. Lee Lewis and H. C. Cheetham | title = Arsanilic Acid | collvol = 1 | collvolpages = 70 | year = 1941 | prep = CV1P0070}}</ref>

:<math>\rm \ C_6H_5NH_2+H_3AsO_4 \rightarrow H_2O_3AsC_6H_4NH_2 +H_2O</math>

* 还原法
由[[对硝基苯胂酸]]经铁粉还原而得。<ref name="chemyq" /> 对硝基苯胂酸可通过[[对硝基苯胺]][[重氮化]]、[[胂化]]制得。

== 用途 ==
用作饲用[[抗菌素]]、医药中间体和分析试剂。早期曾用于治疗皮肤病。

== 参见 ==
* [[苯胂酸]]
* [[对氨基苯胂酸钠]]

== 参考资料 ==
{{reflist}}

[[Category:胂酸]]
[[Category:芳香胺]]