查看“︁墨蝶呤还原酶 (L-苏式-7,8-二氢生物蝶呤形成)”︁的源代码

{{DISPLAYTITLE:墨蝶呤还原酶 (<small>L</small>-苏式-7,8-二氢生物蝶呤形成)}}
{{Infobox enzyme
| Name       = 墨蝶呤还原酶 (<small>L</small>-苏式-7,8-二氢生物蝶呤形成)
| EC_number  = 1.1.1.325
| CAS_number = 9059-48-7
| GO_code    =
| image      = 
| width      = 
| caption    =  
|Acronym=|Systematic_name=<small>L</small>-苏式-二氢生物蝶呤:NADP<sup>+</sup>氧化还原酶|Other_names=}}

'''墨蝶呤还原酶 (<small>L</small>-苏式-7,8-二氢生物蝶呤形成)'''（{{EC number|1.1.1.325}}）是一种[[氧化还原酶]]，其系统名称为'''L-苏式-7,8-二氢生物蝶呤:NADP<sup>+</sup>氧化还原酶'''。<ref>{{cite journal | vauthors = Cho SH, Na JU, Youn H, Hwang CS, Lee CH, Kang SO | title = Sepiapterin reductase producing L-threo-dihydrobiopterin from Chlorobium tepidum | journal = The Biochemical Journal | volume = 340 ( Pt 2) | pages = 497–503 | date = June 1999 | pmid = 10333495 | pmc = 1220277 | doi = 10.1042/0264-6021:3400497 }}</ref><ref>{{cite journal | vauthors = Supangat S, Choi YK, Park YS, Son D, Han CD, Lee KH | title = Expression, purification, crystallization and preliminary X-ray analysis of sepiapterin reductase from Chlorobium tepidum | journal = Acta Crystallographica Section F | volume = 61 | issue = Pt 2 | pages = 202–4 | date = February 2005 | pmid = 16510994 | pmc = 1952253 | doi = 10.1107/S174430910403444X }}</ref>该酶[[催化]]以下[[化学反应]]：

: (1) L-苏式-7,8-二氢生物蝶呤 + NADP<sup>+</sup> <math>\rightleftharpoons</math> 墨蝶呤 + NADPH + H<sup>+</sup>
: (2) L-苏式四氢生物蝶呤 + 2 NADP<sup>+</sup> <math>\rightleftharpoons</math> 6-丙酮酰基-5,6,7,8-四氢蝶呤 + 2 NADPH + 2 H<sup>+</sup>

这种细菌（''{{le|Chlorobaculum tepidum|Chlorobaculum tepidum}}''）酶催化GTP[[从头合成]][[四氢生物蝶呤]]的最后一步。

== 参考资料 ==
{{reflist}}

== 外部链接 ==
* {{MeshName|Sepiapterin+reductase+(L-threo-7,8-dihydrobiopterin+forming)}}

{{醇氧化还原酶类}}
{{酶}}

[[Category:EC 1.1.1]]